Cao Yan
2012
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Journal
Fine Chemical Intermediates
Abstract
1-Aryl-2-pyrrolidinone derivatives are important intermediates for organic synthesis.A novel process was developed for the synthesis of the title compound in an overall yield of 72.2% starting from benzocaine via bromination,nucleophilic substitution and cyclization.The structure of the target compound was confirmed with 1H NMR and MS.This method shows advantages of easy operation,low cost and high yield.