Yang Li-jian
2013
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Journal
Fine Chemical Intermediates
Abstract
Two analogues of 3-oxo-1H-indene-1-carboxylic acid derivatives were synthesized from the corresponding 3-oxo-2,3-dihydro-1H-indene-1-carboxylic acid by monobromination with bromine and subsequent dehydrobromination with DBU.The bromination process conditions were optimized based on the results obtained from orthogonal experiments and the yield was 97%.