Z. Tribak, M. Skalli, Y. Rodi
2017
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Abstract
We report in this paper the reaction of 1, 3-Dipolar Cycloaddition between azides and 5-chloro-1-(prop-2-yn-1-yl)indoline-2, 3-dione in order to synthesize new cycloadducts. The configuration of the products obtained was determined by the magnetic resonance of the proton and carbon. A theoretical study was also carried out, based on the DFT-B3LYP calculation method. The results are in agreement with experimental regiochemistry.