C. Liang, Shuanglin Qin, S. Huang
2016
Citations
0
Influential Citations
0
Citations
Journal
Journal name not available for this finding
Abstract
A synthetic route from 5-(2-Oxo-hexahydro-thieno(3,4-d)imidazol-6-yl)-pentanoic acid (biotin) to 6-Pentyl-tetrahydr o-thieno (3,4-d) imidazol-2-one which have important antibacterial bioactivity was described. The whole route processed in overall 56% yield, including an esterification, a DIBAL-H reduction, a protection and a reduction.