Tong Guo-tong
2007
Citations
0
Influential Citations
0
Citations
Journal
Chemistry World
Abstract
6-Methoxy-2-naphthaldehyde is prepared by Grignard reaction of 6-bromo-2-methoxylnaphthalene,which is synthesized from 2-naphthol via bromination first then reduction and methylation or methylation first then bromination and reduction.The conditions of final treatment and each reaction step are investigated.The final product is purified through silica gel column chromatography and the yield is high with little loss.The overall yield of the two methods is both over 67%.The structure of the title compound was confirmed by IR and()~1H NMR analyse.