Yang Rong-gu
2014
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Journal
Synthetic Materials Aging and Application
Abstract
N,N-dimethyl-4-aminobutanal dimethylacetal is an important intermediate for the synthesis of sumatriptan for migraine drug. In this paper choosed γ-GBL as raw material,through chlorination,Pa /BaSO4 catalytic hydrogenation reduction,followed by amine solution synthesis of the target product,the yield was 50%.