Joseph E. Banning, Jacob Gentillon, P. Ryabchuk
Jul 24, 2013
Citations
1
Influential Citations
25
Citations
Journal
The Journal of organic chemistry
Abstract
A highly chemo- and diastereoselective protocol toward amino-substituted donor-acceptor cyclopropanes via the formal nucleophilic displacement in bromocyclopropanes is described. A wide range of N-nucleophiles, including carboxamides, sulfonamides, azoles, and anilines, can be efficiently employed in this transformation, providing expeditious access to stereochemically defined and densely functionalized cyclopropylamine derivatives.