D. Brown, M. Bruno, R. Davenport
1989
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0
Influential Citations
81
Citations
Quality indicators
Journal
Tetrahedron
Abstract
Abstract Direct substitution of 2-benzenesulphonyl cyclic ethers was studied using a variety of carbon nucleophiles. These nucleophiles included organozinc reagents (derived from aryl, vinyl and alkynyl Grignard reagents) or silyl enol ethers, silyl ketene acetals, allylsilanes and trimethylsilylcyanide in the presence of aluminum chloride. A general selectivity for the formation of the trans-product was observed using 6-subsitituted sulphones.