Hany Mohamed Hassnin
May 31, 2012
Citations
1
Influential Citations
9
Citations
Journal
Arkivoc
Abstract
Chloro-6-ethyl-3-nitropyrano(3,2-c)quinoline-2,5(6H)-dione (3) was obtained by nitration followed by chlorination of 4-hydroxypyranoquinoline-2,5-dione 1. Substitution reactions of compound 3 with various nucleophiles, namely: sodium azide, amines, thiophenol and malono- nitrile, led to a series of novel 4-sustituted-3-nitropyranoquinolinones. Also, nucleophilic reactions of compound 3 with hydrazine, cyanoguanidine and S-methylisothiourea, involving ring opening-ring closure of the pyranoquinolinedione nucleus, are described.