H. Tajmir-Riahi
1986
Citations
0
Influential Citations
30
Citations
Journal
Journal of Inorganic Biochemistry
Abstract
Abstract Interaction between D -glucuronic acid and Zn(II), Cd(II), and Hg(II) metal ion salts has been studied in solution and solid complexes of the type M( D -glucuronate)X · n H 2 O and M( D -glucuronate) 2 · n H 2 O, where M = Zn(II), Cd(II), and Hg(II), X = Cl − or Br − , and n = 0–2 were isolated and characterized. Spectroscopic and other evidence indicated that in the metal-halide-sugar complexes the Zn(II) and Cd(II) ions bind to two D -glucuronate moieties via 06, 05 of the carboxyl oxygen atoms of the first and 04, 06' of hydroxyl and carbonyl groups of the second as well as to two H 2 O molecules, whereas in the corresponding M( D -glucuronate) 2 · n H 2 O salts, the metal ions are bonded to two sugar anions through 06 and 06' of the ionized carboxyl groups and two water molecules, resulting in a six-coordination around each metal cation. The Hg(II) ion binds to 06 and 05 oxygen atoms of a sugar anion and to a halide anion or water molecule, in the Hg( D -glucuronate)X·nH 2 O compounds, while in the corresponding metal-glucuronate salt mercury is bonded to 06 and 06' of the two glucuronate anions with four-coordination around the Hg(II) ion. The β-anomer sugar conformation is predominant in the free acid and in these series of metal-sugar complexes.