P. Morgan, R. Mccague, A. Whiting
Jun 25, 1999
Citations
0
Influential Citations
5
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Tosyl cyanide is activated by titanium(IV) chloride to generate a tolylsulfinyl chloride equivalent, which readily stereo- and regio-specifically adds to certain alkenes to provide β-chlorosulfoxides. These chlorides rapidly hydrolyse on silica gel to provide β-hydroxysulfoxides in stereocontrolled manner.