B. Trost, Christopher A. Kalnmals
Aug 27, 2019
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0
Influential Citations
58
Citations
Journal
Chemistry
Abstract
Sulfones are flexible functional groups that can act as nucleophiles, electrophiles, or even radicals. Changing the reaction conditions can completely alter the reactivity of a sulfonyl group, and as a result, molecules bearing multiple sulfones are versatile building blocks. This review highlights the unique ability of 1,1- and 1,2-bis(sulfones) to masquerade as a vast array of reactive synthons - including methane polyanions, vinyl cations, and all-carbon dipoles - that would be difficult or impossible to access directly.