Xiaohu Ouyang, N. Tamayo, A. Kiselyov
Mar 5, 1999
Citations
0
Influential Citations
33
Citations
Journal
Tetrahedron
Abstract
Abstract Efficient assembly of dibenz[b,f]oxazepin-11(10H)-ones utilizing the SNAr of fluorine in 2-fluoro-5-nitrobenzoic acid with the OH of various 2-aminophenols on solid support is reported. The flexibility of this synthesis, as well as the excellent purity (>90%) of the final products are the distinctive characteristics of the resulting library.