Yong Chen, Kun Han, Yu Liu
Jul 1, 2007
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Influential Citations
43
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Journal
Bioorganic & medicinal chemistry
Abstract
A water-soluble 8-aminoquinolino-beta-cyclodextrin/1-adamantaneacetic acid (1/ADA) system is prepared in situ and exhibits a unique switch-on fluorescence response to Zn(2+) over other common metal ions. Spectrophotometric studies demonstrate that this system can strongly coordinate Zn(2+) through a cyclodextrin/substrate/metal triple recognition mode, and the resulting 1/ADA/Zn(2+) ternary complex emits the blue-green fluorescence (lambda=490nm) that can be easily distinguished by eyes in aqueous solution. Significantly, the switch-on fluorescence response of 1/ADA to Zn(2+) is barely affected by various metal ions except Cu(2+). As a result, this system can behave as an efficient supramolecular fluorescence sensor for Zn(2+) in water.