R. H. Shah, F. Loewus
Oct 1, 1970
Citations
0
Influential Citations
3
Citations
Journal
Journal of Labelled Compounds and Radiopharmaceuticals
Abstract
1-O- and 5-O-Methyl-14C-myo-inositols (methyf-14C-bornesitol and -sequoyitol) were synthesized by methylation of appropriately blocked myo-inositol derivatives with methyl = 14C iodide and potassium hydroxide. The benzyl blocking groups of 1-O-methyl-14C-3,4,5, 6-tetra-O-benzyl-DL-myo-inositol and 1,2,3,4, 6-penta-O-benzyl-5-0-methyl-14C-myo-inositol were cleaved by hydrogenolysis catalyzed by palladium on carbon-palladium chloride (5 : 1) to obtain the 1-O- and 5-O-methyl-14C-myo-inositols respectively.