H. Kasai, S. Nishimura
Jul 1, 1982
Citations
0
Influential Citations
15
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
The strongly mutagenic compound, 2-amino-3,4-dimethyl-3H-imidazo[4,5-f]quinoline (Me-IQ), isolated from broiled sardines was synthesized from 6-amino-7-methylquinoline. Several structurally related compounds were also synthesized to clarify the structure-activity relationship. Some of them also showed strong mutagenic activity towards Salmonella typhimurium TA98.