Emma-Claire Elliott, Elizabeth R. Bowkett, J. Maggs
Sep 22, 2011
Citations
0
Influential Citations
29
Citations
Journal
Organic letters
Abstract
Efficient procedures for the synthesis of benzo-fluorinated dibenz[b,f]azepines (iminostilbenes) from fluorinated isatins or indoles using a number of ring-expansion reactions are described. A range of mono- and difluorinated analogues is accessible, and the syntheses can deliver gram quantities of the final products, which are precursors of fluoro analogues of the important anticonvulsant carbamazepine.