Wu Chang-tai
2001
Citations
0
Influential Citations
0
Citations
Journal
Wuhan University Journal
Abstract
L-Valinol (1a) and L-Isoleucinol (1b) were synthesized by the reaction of L-Valine and L-Isoleucine with NaBH 4, respectively. The reaction of 1a and 1b with TsCl gave 3-methyl-2-tosylamino-butanol-tosylate(2a) and 3-methyl-2-tosylamino-petanol-tosylate(2b), respectively. The cyclination of 2a and 2b in the presence of KOH obtained chiral aziridine reagents 3a and 3b, respectively. The synthetic condition of intermediates 2 was studied. The rotatory characteristic of 3a,b was measured. All intermediates and chiral aziridines were identified by elemetal analysis, 1H NMR and MS.;