Tan Zhi
1993
Citations
0
Influential Citations
0
Citations
Journal
Chinese Journal of Organic Chemistry
Abstract
(1R,2R) trans-1,2-cyglopropanedicarboxylic acid (3) and (1R,2R) trans-3,3-dimethyl-1,2-cyclopropanedicacid (5) were prepared by reaction of (-) dim-enthyl fumarate with gem-dihalides (CH_2Br_2, CH_3CCl_2CH_3) catalyzedbby cobalt (0), nickel(0) complex and Zn under ultrasonic waves. The chemical and optical yield of 3 increasedto 79.5% and 78% respectively. The chemical and opticl yield of 5 increased to 55.3%and 47.8% respectively. Addition of bidentate ligands was useful for CH_2CBr_2 system, butnot for CH_3CCl_2CH_3 system. Two optical isomers of cyclopropane derivatives were seperatedfrom HPLC by chiral column PTrMA.