Li, Wen-ming, Wang
2008
Citations
0
Influential Citations
1
Citations
Journal
Chinese Journal of Structural Chemistry
Abstract
The title compounds (S)-methyl-2-(4-R-phenylsulfonamido)-3-(1H-indol-3- yl)propanoate (R = H (1), Cl (2)) have been synthesized and their crystal structures also have been determined by X-ray single-crystal diffraction. Compound 1 (C18H18N2O4S) belongs to orthor- hombic, space group P212121 with a = 9.6348(14), b = 11.1517(17), c = 16.412(3) , V = 1763.4(5) 3, Mr = 358.40, Z = 4, Dc = 1.350 g/cm3, μ = 0.209 mm–1, F(000) = 752, R = 0.0348 and wR = 0.0714. Compound 2 (C18H17ClN2O4S) crystallizes in orthorhombic, space group P212121 with a = 9.3128(14), b = 10.9655(16), c = 17.783(3), V = 1815.9(5) 3, Mr = 392.85, Z = 4, Dc = 1.437 g/cm3, μ = 0.352 mm–1, F(000) = 816, R = 0.0389 and wR = 0.0845. The absolute structure Flack parameters X of compounds 1 and 2 are –0.03(8) and –0.06(7), respectively. X-ray analysis reveals that the crystal structures of these two compounds both involve two intermolecular N–H…O hydrogen bonds.