T. Fujita, S. Watanabe, K. Suga
Sep 14, 1982
Citations
0
Influential Citations
6
Citations
Journal
Journal of Chemical Technology & Biotechnology
Abstract
5-Methyl-2-isopropyl-4-hexenoic acid, dihydrolavandulic acid (III), was synthesised in 65% yield from 3-methylbutanoic acid and isoprene with sodium naphthalenide in the presence of N,N,N′,N′-tetramethylethylenediamine. Reduction of III with lithium aluminum hydride gave 5-methyl-2-isopropyl-4-hexen-l-ol, dihydrolavandulol (IV) (85% yield). Oxidation of IV with pyridinium chlorochromate gave 5-methyl-2-isopropyl-4-hexenal, dihydrolavandulyl aldehyde (V) (81 % yield).