Heidi Antunes, L. C. Fardelone, J. A. Rodrigues
Sep 6, 2004
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0
Influential Citations
15
Citations
Journal
Tetrahedron-asymmetry
Abstract
Abstract Enantioselective reductions of 2-X-1-(1,3-benzodioxol-5-yl)-1-ethanones, (X = Cl, Br, N 3 ) by Rhodothorula glutinis CCT 2182 afforded the corresponding ( R )-ethanols in good to excellent yields (57–99%) and excellent enantiomeric excesses (>99%). These alcohols may be used as raw materials for the preparation of the pharmaceuticals ( R )-(−)-epinephrine, ( R )-(−)-norepinephrine and ( R )-(−)-isoproterenol.