K. Matsuo, J. Kawanishi, M. Kobayashi
Oct 1, 2005
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0
Influential Citations
4
Citations
Journal
Heterocycles
Abstract
2-Cyclohexyl-1,3,4,5-tetrahydro-10H-pyrrolo[3,4-b][1,5]benzodiazepine-1,4-dione was synthesized by heating a solution of ethyl 1-cyclohexyl-2,3-dioxopyrrolidine-4-carboxylate and o-phenylenediamine in acetic acid. Alkylation and acylation of the synthesized compound were examined. 4-Aryl-2-cyclohexyl-1,3,4,10-tetrahydropyrrolo[4,3-c] [1,5]benzothiazepin- -ones were synthesized by Michael addition of 2-aminothiophenol to 4-arylidene-1-cyclo-hexyl-2,3-dioxopyrrolidines and concomitant dehydrative cyclization.