N. O. Saldabol, S. Giller, L. N. Alekseeva
Feb 1, 1967
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Journal
Pharmaceutical Chemistry Journal
Abstract
Abstract2-(5-Nitro-2-furyl)-substituted imidazo-[1,2-b]-benzothiazole and imidazo-[1,2-a]-pyridine, 6-(5-nitro-2-furyl)-substituted 3-(2-furyl)-imidazo-[1,2-b]-1,2,4-triazine, 2-methyl- and 2-(2-furyl)-imidazo-[2,1-b]-1,3,4-thiadiazoles and also 2,6-di-(5-nitro-2-furyl)-imidazo-[2,1-b]-1,3,4-thiadiazole were obtained from bromomethyl-5-nitro-2-furyl ketone and the corresponding heterocyclic amines with amidine structure. The greatest antimicrobial effect among the imidazo compounds is exhibited by 2-(5-nitro-2-furyl)-imidazo-[1,2-a]-pyridine but in most cases it has a weaker effect than furazolidone.