S. Nishiyama, S. Yamamura, K. Hasegawa
Nov 11, 1991
Citations
0
Influential Citations
7
Citations
Journal
Tetrahedron Letters
Abstract
Trans- and cis-3-methoxy-4-methylthio-2-piperidinethiones previously proposed for raphanusanins as a light-induced growth inhibitor, have been synthesized starting from the known α,β-unsaturated lactam. However, the spectral data of the synthetic compounds are incompatible with those of natural ones. Thus, reexamination of 1H and 13C NMR spectra of the natural samples has led to correct structures for raphanusanins. The synthetic compounds also show a growth inhibitory activity.