V. M. Muzalevskiy, A. V. Shastin, E. Balenkova
Dec 1, 2011
Citations
0
Influential Citations
8
Citations
Journal
Journal of Fluorine Chemistry
Abstract
Abstract A novel synthetic approach towards α-trifluoromethyl-phenethylamines was elaborated by reduction of the electron deficient β-aryl-α-trifluoromethyl enamines and imines with sodium cyanoborohydride in the presence of trifluoroacetic acid. The starting imines were prepared by the reaction of primary amines with β-aryl-α-trifluoromethyl enamines or β-chloro-β-(trifluoromethyl)styrenes.