Y. Kuroki, Daisuke Asada, Y. Sakamaki
Jun 12, 2000
Citations
0
Influential Citations
19
Citations
Journal
Tetrahedron Letters
Abstract
Abstract The highly enantioselective synthesis of 1,1,1-trifluoroalkan-2-ols has been achieved by hydrogenating 1,1,1-trifluoroalkan-2-one enol acetates in the presence of chiral ruthenium catalysts. An enol acetate, 2-acetoxy-3,3,3-trifluoro-1-(phenylthio)propene, can be successfully transformed into enantiomerically pure trifluorolactic acid.