Liu Xiu-jie
2010
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0
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Journal
Journal of tianjin University of Technology
Abstract
1,1,4,4,6-pentamethyl-1,2,3,4-tetrahydronaphthalene is an important intermediate of synthesizing bexarotene.2,5-dimethyl-2,5-hexanediol as raw material,1,1,4,4,6-pentamethyl-1,2,3,4-tetrahydronaphthalene was synthesized by halogenated reaction and Friedel-Crafts alkylation.Meanwhile,the reacting mechanisms of halogenated and Friedel-Crafts alkylation were exploited and discussied,and of the factors which affected the reaction was also introduced here.