Teng Da-wei
2010
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Journal
Science Technology and Engineering
Abstract
1,2,3,4-tetrahydro-2,6-naphthyridine in total yield of 47.3% was synthesized from 2-methylpyrazine by a six-step reaction of condensation,elimination,addition of double bond with amine,protection of amino group,cyclic addition/exclusion and removal of protection group.The structure is confirmed by 1H-NMR,13C-NMR,Elemental analysis and MS.