P. A. Soni, P. Gupta, C. Maurya
May 20, 2015
Citations
0
Influential Citations
3
Citations
Journal
Tetrahedron Letters
Abstract
1,2-Diones are important organic intermediates and substrates for many organic reactions. In this Letter, we describe a newer method for the synthesis of 1,2-diones from corresponding 1,2-diols using inexpensive iron(III) nitrate nonahydrate under microwave irradiations. The new protocol is efficient, rapid and high yielding that has circumvented the handling and use of toxic and expensive reagents. Moreover, exclusion of any organic solvent and solid support made this method an attractive and useful alternative to the existing methods for the synthesis of 1,2-diones. The process has been extended for the synthesis of a variety of diones and effect of electronic and steric factors on the reaction profile has been discussed.