S. Mai
2005
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Journal
Fine Chemical Intermediates
Abstract
1-(3-chlorophenyl) piperazine was synthesized from 3-chloroaniline and bis- (2-chloroethyl) amine hydrochloride, and reacted with l-bromo-3-chloropropane to give l-(3-chlorophenyl) -4- (3-chloropropyl) piperazine hydrochloride. The overall yield is 45.7%.