E. Boroda, R. Kański, M. Kańska
Apr 1, 2003
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0
Influential Citations
6
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Journal
Journal of Labelled Compounds and Radiopharmaceuticals
Abstract
The synthesis of selectively 14C-labeled l-tryptophan and its derivative 5-hydroxy-l-tryptophan using chemical and multienzymatic methods is reported. The mixture containing [1-14C[-dl-alanine, indole or 5-hydroxyindole has been converted to [1-14C]-l-tryptophan or 5′-hydroxy-[1-14C]-l-tryptophan, respectively, in a one-pot multienzymatic reaction using four enzymes: d-amino acid oxidase, catalase, glutamic-pyruvic transaminase and tryptophanase. Copyright © 2003 John Wiley & Sons, Ltd.