Ángel Rentería-Gómez, Rocío Gámez-Montaño
Nov 1, 2016
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Abstract
A series of nine new 1,5-disubstituted-1H-tetrazoles were synthesized via MCR Ugi-azide in moderate to excellent yields (80 - 95%), using propargyl amine as component varying the aldehyde and isocyanide components. 1,5-DS-T are useful heterocyclic moieties present in many bioactive compounds and drugs. Morever 1,5-DS-T are used as bidentate ligands, in coordination chemistry, metal-organic framework science, bioimaging, photo-imaging, explosives, propellants, high energy materials.