Andrew V. Mossine, Allen F. Brooks, Katarina J. Makaravage
Nov 14, 2015
Citations
4
Influential Citations
174
Citations
Quality indicators
Journal
Organic Letters
Abstract
A copper-mediated radiofluorination of aryl- and vinylboronic acids with K18F is described. This method exhibits high functional group tolerance and is effective for the radiofluorination of a range of electron-deficient, -neutral, and -rich aryl-, heteroaryl-, and vinylboronic acids. This method has been applied to the synthesis of [18F]FPEB, a PET radiotracer for quantifying metabotropic glutamate 5 receptors.