K. Kobayashi, K. Hashimoto, T. Ukon
Feb 1, 2008
Citations
0
Influential Citations
7
Citations
Journal
Synthesis
Abstract
A new and simple method for the preparation of 1-aminonaphthalene-2-carbonitrile derivatives has been developed. When 2-(1-arylethenyl)benzonitriles are treated with 2-lithioacetonitrile, 1 -amino-4-aryl-3,4-dihydronaphthalene-2-carbonitriles are obtained in good yields. The reaction of 2-(1-aryl-2-methoxyethenyl)benzonitriles with 2-lithioacetonitrile leads to the formation of l-amino-4-arylnaphthalene-2-carbonitriles in fair-to-good yields.