I. Uemura, Ken‐ichi Yamada, Kayoko Sugiura
Apr 17, 2001
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Influential Citations
10
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Journal
Tetrahedron-asymmetry
Abstract
Abstract A highly stereoselective synthesis of (2R,3S)-3,4-epoxy-3-methyl-1-(triphenylmethyl)oxybutan-2-ol 3, which is a substructure found in some naturally-occurring bioactive compounds, was achieved starting from commercially available 3-methyl-2-buten-1-ol 4 in three steps, using two applications of the Sharpless asymmetric epoxidation as the key stereochemistry establishing reactions.