T. Hagen, J. Cook
1988
Citations
0
Influential Citations
18
Citations
Journal
Tetrahedron Letters
Abstract
Abstract The six step synthesis of the cytotoxic antileukemic alkaloid 1-methoxy canthine-6-one 2 is described. The pivotal steps are represented by the oxidation (DDQ) of 9 to afford the 3-acylindole 14 and the conversion of 11 into the 4-methoxy-1-alkyl β-carboline 15 .