B Ravinder Reddy, Sayed Jalal, P. Borkar
Mar 20, 2013
Citations
0
Influential Citations
6
Citations
Journal
Tetrahedron Letters
Abstract
Abstract The homoallylic alcohol tethered with a benzylic hydroxyl group, that is, ( E )-4-(2-(hydroxymethyl)phenyl)but-3-en-1-ol undergoes smooth Prins bicyclization with various aldehydes in the presence of 20 mol % Sc(OTf) 3 and 4 A MS at 80 °C to afford a novel series of 1-(tetrahydrofuran-3-yl)-1,3-dihydroisobenzofuran derivatives in good yields with high diastereoselectivity.