O. Calvez, A. Chiaroni, N. Langlois
Dec 17, 1998
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0
Influential Citations
28
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Journal
ChemInform
Abstract
Abstract N -methoxy- N -methylamide derived from ( S )-methylpyroglutamate was prepared in good yield and allowed the addition of Grignard reagents. Erythro ( 2S )-1-benzyl-2-hydroxybenzyl pyrrolidine obtained by this way was converted into ( 2S,3R )-1-benzyl-3-hydroxy-2-phenylpiperidine and its chloro analog.