T. Karabasanagouda, A. Adhikari, Ramgopal Dhanwad
2008
Citations
1
Influential Citations
22
Citations
Journal
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry
Abstract
A series of new 2-{[4-(alkylthio)phenoxy]methyl}-4-substituted-1,3-thiazoles 4a-q, 6a-j have been synthesized from ethyl [4-(alkylthio)phenoxy]acetates la,b through multi-step reaction sequence. The structures of new compounds have been established on the basis of their elemental analysis and IR, 1 H and 13 C NMR and mass spectral data. Selected title compounds have been evaluated for anti-inflammatory activity and in vitro antibacterial testing against two pathogenic strains and antifungal screening against two fungi.