S. Katayama, Toshio Watanabe, M. Yamauchi
Mar 15, 1993
Citations
0
Influential Citations
9
Citations
Journal
Chemical & Pharmaceutical Bulletin
Abstract
A convenient synthesis of a variety of 2, 4-cyclohexadien-1-ones 3-7 is described. Reaction of various phenols 2 having appropriate substituents with an excess of S, S-dimethylsuccinmidosulfonium chloride (Corey-Kim reagent, 1)in the presence of triethylamine proceeded with regioselective methylthiomethylation to give methylthiomethyl, bis(methylthiomethyl), or tris(methylthiomethyl)-2, 4-cyclohexadien-1-ones 3-7 in satisfactory yields.