Wang Guo-xi
2004
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Journal
Applied Science and Technology
Abstract
2,4-Dichlorofluorobenzene is an organic intermediate for synthesizing ciprofloxacin,a broadspectrum antibiotics.With increasing consumption of ciprofloxacin,the demand for 2,4-Dichlorofluorobenzene is increasing at home and abroad.2,4-Dichlorofluorobenzene is prepared by diazotizating of 2,4-dichloro aniline and substituting of 2,4-dichloro diazo benzene with fluorinion.The purity is 99.2% and the yield is (50.2%.)This new process is simple and suitable for industrial production.