Shunsuke Nakamura, T. Takase, Dai Oyama
Apr 22, 2019
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Journal
Synthetic Communications
Abstract
Abstract This study reports the synthesis of a methoxy-substituted 2,6-di(1,8-naphthyridin-2-yl)pyridine using Friedländer methodology. The functionalization at the 4-carbon of the methoxy-substituted derivative was confirmed by X-ray structural analysis. Finally, the methyl ether protecting group was cleaved to obtain 2,6-di(1,8-naphthyridin-2-yl)pyridine-4-ol. Using the compounds, coordination behavior to ruthenium(II) center was also examined. Graphical Abstract