B. Juma, M. Adeel, A. Villinger
Mar 31, 2008
Citations
0
Influential Citations
5
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Acetal-protected (2,4-dioxocyclohex-1-yl)acetic acid derivatives were prepared by the allylation of dilithiated 1,3-cyclohexane-1,3-diones, by the protection of the carbonyl groups and by the oxidation of the alkene. The products were then transformed, by amide formation and subsequent cyclization, into 2,6-dioxo-1,2,3,4,5,6-hexahydroindoles, which represent important intermediates for the synthesis of various alkaloids.