Samad Khaksar, Ahmad Rouhollahpour, Saeed Mohammadzadeh Talesh
Sep 1, 2012
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Journal
Journal of Fluorine Chemistry
Abstract
Abstract A highly efficient one-pot three-component regioselective synthesis of 2-amino-3-cyano-4 H -chromene and tetrahydrobenzo[ b ]pyran derivatives has been developed by annulation of aldehydes, malononitrile, and resorcinol or dimedone under reflux conditions in 2,2,2-trifluoroethanol without the use of a catalyst or any other additive.