Y. Yamauchi, S. Hara, H. Senboku
Jan 9, 2010
Citations
0
Influential Citations
31
Citations
Journal
Tetrahedron
Abstract
Abstract Electrochemical carboxylation of (1-bromo-2,2,2-trifluoroethyl)arenes resulted in an efficient fixation of carbon dioxide to give the corresponding 2-aryl-3,3,3-trifluoropropanoic acids in good yields, and the present reactions were successfully applied to the synthesis of β,β,β-trifluorinated non-steroidal anti -inflammatory drugs (NSAIDs).