A. Smolobochkin, A. Gazizov, V. Syakaev
May 18, 2017
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Influential Citations
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Journal
Monatshefte für Chemie - Chemical Monthly
Abstract
Herein we report the synthesis of previously unknown 2-arylpyrrolidine-1-carboxamides containing aminophenol moiety via a novel approach developed by us, namely, acid-catalyzed cyclization of (4,4-diethoxybutyl)ureas in the presence of 3-aminophenol. The proposed approach benefits from mild reaction conditions, use of inexpensive and common solvents and catalyst, and allows to obtain target compounds with good to high yields.Graphical abstract