G. Madhusudhan, Raman Vysabhattar, R. N. Reddy
2009
Citations
0
Influential Citations
0
Citations
Journal
Organic Chemistry: An Indian Journal
Abstract
A facile and efficient synthesis of 2-bromo-5-methyl pyrazine is described. The synthetic scheme involves the conversion of 5-methylpyrazine-2-carboxylic acid to the corresponding amide which on Hofmann degradation gives the amine compound. This amine compound on diazotization followed by in-situ bromination produces the targeted 2-bromo-5-methyl pyrazine.