E. O. Leonard, C. G. Skinner, W. Shive
1961
Citations
0
Influential Citations
5
Citations
Journal
Archives of biochemistry and biophysics
Abstract
Abstract The effects of a 2-fluoro substituent and of the replacement of the imidazole ring by a triazole ring upon the biological activities of a 6-(substituted)purine were determined. The 2-fluoro and 2-amino-8-aza analogs of 6-benzylaminopurine were synthesized, and the 2-fluoro but not the 2-amino-8-aza derivative was found to replace kinetin in stimulating the rate of seed germination. 2-Fluoro-6-benzylaminopurine is appreciably more toxic to microbial growth than are either 2-amino-6-benzylamino- or 6-benzylaminopurine.