A. Kel'in, V. Gevorgyan
Jan 11, 2002
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Influential Citations
143
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Journal
The Journal of organic chemistry
Abstract
A mild, general, and efficient method for the synthesis of 2-monosubstituted and 2,5-disubstituted furans via the CuI-catalyzed cycloisomerization of alkynyl ketones was developed. It was demonstrated that furans containing both acid- and base-labile groups could be easily synthesized using this methodology. A plausible mechanism for this transformation is proposed.